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Clinical Scenario 8


James is a 65 year old man with a 10 year history of hypertension and Type 2 diabetes. He smokes 5/day. He drinks one bottle of wine per day. He woke up this morning with some weakness and clumsiness in his left hand. A CT scan was normal but now an MRI is shown below. He stopped taking his BP medications 3 years ago as he was depressed.

Click to see his scan

What are the characteristic features seen

  • There is restricted diffusion on the left side of the pons
  • This is rich in corticospinal fibres which will cross over in the medulla below
  • Damage to these will cause right sided arm/leg weakness
  • It can also affect fibres from the cerebellum causing the limb to be ataxic and clumsy
  • The infarct does not cross the midline which is typical of these vascular lesions
  • It is caused by occlusion of a pontine perforator branch from the basilar artery
  • Commonly seen with hypertension and diabetes
  • The CT shows calcification of the basilar artery

3.What is the management

  • Ongoing Stroke rehabilitation
  • Optimising treatment of his BP and diabetes
  • Mood assessment
  • Smoking cessation
  • Reducing alcohol intake
  • Antiplatelet therapy
  • Statin would be considered as he likely has vascular disease

Next: >> Clinical Scenario 2


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